Epiphen Tablets 30 mg (1000 pack)
We require the original prescription before we can dispense Epiphen - sadly, we cannot currently dispense against a fax or email for this product.
Contains phenobarbitol for the controol of epilepsy in dogs, tablets are not meant to be divided. Read more
We require the original prescription before we can dispense Epiphen - sadly, we cannot currently dispense against a fax or email for this product.
Contains phenobarbitol for the controol of epilepsy in dogs, tablets are not meant to be divided.
Visit www.myvetmeds.co.uk / dog / epilepsy / epiphen-tablets-30-mg-1.htm
Product Description
About Epiphen Tablets 30 mg (1000 pack)
We require the original prescription before we can dispense Epiphen - sadly, we cannot currently dispense against a fax or email for this product.
Contains phenobarbitol for the controol of epilepsy in dogs, tablets are not meant to be divided.
Please note: images are for illustration purposes only and pack sizes/strengths and new packaging styles may not be reflected in the image shown.
Directions For Use
Directions for Use
The required dosage will differ to some extent between individuals and with the nature and
severity of the disorder.
Dogs should be dosed orally, starting with a dose of 2-5mg per kg bodyweight per day. The
dose should be divided and administered twice daily.
Steady state serum concentrations are not reached until 1-2 weeks after treatment is initiated.
The full effect of the medication does not appear for two weeks and doses should not be
increased during this time.
Vm 08007/4067
February 2008
3
If seizures are not being controlled, the dosage may be increased by 20% at a time, with
associated monitoring of serum Phenobarbital levels. The Phenobarbital serum concentration
may be checked after steady state has been achieved, and if it is less than 15?g/ml the dose
may be adjusted accordingly. If seizures recur the dose may be raised up to a maximum serum
concentration of 45?g/ml. High plasma concentrations may be associated with hepatotoxicity.
Blood samples could be taken at the same time to allow plasma Phenobarbital concentration to
be determined preferably during trough levels, shortly before the next dose of Phenobarbital is
due.
For accuracy of dosing, dogs under 12kg should commence therapy with Epiphen Solution.
Tablets are not intended to be subdivided.
Active Ingredient
Epiphen Tablets 30 mg (1000 pack) ingredients
Active ingredient 30mg of Phenobarbital per tablet.
Side Effects
Side effects of Epiphen Tablets 30 mg (1000 pack)
Occasionally polyphagia, polyuria and polydipsia have been reported, but these effects
are usually transitory and disappear with continued medication.
Toxicity may develop at doses over 20mg/kg/day or when serum Phenobarbital levels
rise above 45?g/ml.
In the light of isolated reports describing hepatotoxicity associated with combination
anticonvulsant therapy, it is recommended that:-
1. Hepatic function is evaluated prior to initiation of therapy (e.g. measurement of
serum bile acids).
2. Therapeutic Phenobarbital serum concentrations are monitored to enable the
lowest effective dose to be used. Typically concentrations of 15-45?g/ml are
effective in controlling epilepsy.
3. Hepatic function is re-evaluated on a regular (6 to 12 month) basis.
4. Seizure activity is re-evaluated on a regular basis.
Additional Data
Epiphen Tablets 30 mg (1000 pack) specification
| Specification: | Detail: |
|---|---|
| Associated Documents: |
Click here to preview |
| Pack Size: | 1000 pack |
| Brands: | Vetoquinol |
| Product Form: | tablet |
| External Link: | http://www.noahcompendium.co.uk/Intervet_Schering-Plough/documents/S3636.html |
| Strength/Size: | 30 mg |
