Galastop Oral Solution (7 ml)
Cabergoline is an ergoline derivative with a potent, selective and long-lasting inhibitory effect on prolactin secretion. Prolactin is the key hormone for lactogenesis and for the initiation and maintenance of lactation after parturition. Furthermore the aetiology of false pregnancy is currently thought... Read more
Cabergoline is an ergoline derivative with a potent, selective and long-lasting inhibitory effect on prolactin secretion. Prolactin is the key hormone for lactogenesis and for the initiation and maintenance of lactation after parturition. Furthermore the aetiology of false pregnancy is currently thought to be mediated by rising prolactin levels stimulated by falling progesterone levels during the course of metoestrus.
Treatment of false pregnancy in bitches
Inhibition of prolactin secretion by cabergoline results in a rapid resolution of the signs of false pregnancy, including lactation and behavioural changes.
Suppression of lactation in bitches
Suppression of lactation in the bitch may be required under certain clinical circumstances (for example following removal of puppies soon after birth, or following early weaning). Inhibition of prolactin secretion by Galastop ® results in a rapid cessation of lactation and a reduction in the size of the mammary glands.
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Product Description
About Galastop Oral Solution (7 ml)
Cabergoline is an ergoline derivative with a potent, selective and long-lasting inhibitory effect on prolactin secretion. Prolactin is the key hormone for lactogenesis and for the initiation and maintenance of lactation after parturition. Furthermore the aetiology of false pregnancy is currently thought to be mediated by rising prolactin levels stimulated by falling progesterone levels during the course of metoestrus.
Treatment of false pregnancy in bitches
Inhibition of prolactin secretion by cabergoline results in a rapid resolution of the signs of false pregnancy, including lactation and behavioural changes.
Suppression of lactation in bitches
Suppression of lactation in the bitch may be required under certain clinical circumstances (for example following removal of puppies soon after birth, or following early weaning). Inhibition of prolactin secretion by Galastop ® results in a rapid cessation of lactation and a reduction in the size of the mammary glands.
Please note: images are for illustration purposes only and pack sizes/strengths and new packaging styles may not be reflected in the image shown.
Directions For Use
Directions for Use
Galastop ® should be administered orally either directly into the mouth or by mixing with food.
The dosage is 0.1 ml/kg bodyweight (equivalent to 5 ?g/kg body weight of cabergoline) once daily for 4-6 consecutive days, depending on the severity of the clinical condition.
For dogs less that 5 kg bodyweight it is advisable to measure the dosage in drops, 3 drops being equivalent to 0.1 ml.
If the signs fail to resolve after a single course of treatment, or if they recur after the end of treatment, then the course of treatment may be repeated.
For treatment of false pregnancy, clinical studies have demonstrated efficacy between 80-100%. Behavioural signs are alleviated first, followed by reduction in mammary gland enlargement, then finally suppression of lactation.
Active Ingredient
Galastop Oral Solution (7 ml) ingredients
A pale yellow, viscous non aqueous solution for oral administration containing 50 ?g/ml cabergoline in a miglyol base.
Side Effects
Side effects of Galastop Oral Solution (7 ml)
Do not use in pregnant animals since Galastop ® may cause abortion. Do not use in lactating bitches unless suppression of lactation is required.
Galastop ® may induce transient hypotension in treated animals. Do not use in animals concurrently being treated with hypotensive drugs. Do not use directly after surgery whilst the animal is still under the influence of the anaesthetic agents.
Since cabergoline exerts its therapeutic effect by direct stimulation of dopamine receptors, Galastop ® should not be administered concurrently with drugs which have dopamine antagonist activity (such as phenothiazines, butyrophenones), as these might reduce its prolactin inhibiting effects.
Vomiting or anorexia may occur after the first one or two doses in a small proportion of cases. There is no need to discontinue treatment unless vomiting is severe or it persists beyond the second dose.
In some animals a degree of drowsiness may be seen in the first 2 days of dosing.
The experimental data indicate that a single overdose with Galastop ® might result in an increased likelihood of post-treatment vomiting, and possibly an increase in post-treatment hypotension. General supportive measures should be undertaken to remove any unabsorbed drug and maintain blood pressure, if necessary. It is unlikely that the administration of dopamine antagonist drugs would be necessary, but this course of action could be considered.
For animal treatment only. Keep out of reach and sight of children.
Additional Data
Galastop Oral Solution (7 ml) specification
| Specification: | Detail: |
|---|---|
| Pack Size: | 7 ml |
| Brands: | Ceva Animal Health |
| Product Form: | drops |
| External Link: |
http://www.noahcompendium.co.uk/Ceva_Animal_Health_Ltd/documents/S4306.html |
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Galastop for rabbits
D MacLeod on 26th August 2011
I have been given this to treat my doe/female rabbit in false pregnancy of which is the same course of 5 days per drops per weight and have found it works a treat and thanks
Q & A
- Q. Is there presently an off label use in cats? Will it prevent cats from coming into heat or shorten the duration?
- A.
As far as I'm aware, the only off-label use in cats (and only when used under the Cascade system) is for causing a queen to abort - and I understand that it has significant side effects. Your vet would have to make the cost/benefit analysis as to whether it was appropriate to use in a specific case, but I must say that I've never seen it used it in cats.
David Harris BVSc MRCVS
MyVetMeds - Q. vomiting and not steady on her legs is this normal? she as had this treatment before and she was fine.
thanks.
tara. - A.
Hi Tara,
Vomiting and drowsiness are quite common after the first dose - but if it's carrying on beyond this, especially as she's had this medicine before with no problems, I would strongly advise that you contact your vet and have a chat with them about it. It may be that your dog's dose needs to be checked or changed.
I hope this helps,
David Harris BVSc MRCVS
MyVetMeds Dispensing Vets
