Prednidale Tablets 25 mg (100 tablets)

Prednidale 25 is indicated in the treatment of inflammatory and allergic conditions in dogs.
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Product Description
About Prednidale Tablets 25 mg (100 tablets)
Prednidale 25 is indicated in the treatment of inflammatory and allergic conditions in dogs.
Please note: images are for illustration purposes only and pack sizes/strengths and new packaging styles may not be reflected in the image shown.
Directions For Use
Directions for Use
Dose: 0.1-2.0 mg prednisolone per kg body weight per day. The lowest effective dose must be used.
These tablets are not appropriate when dosing small dogs at the lower recommended dosage rates and the 5 mg tablet size may be required.
Treatment should not be withdrawn suddenly. A gradual reduction of dosage is recommended.
Dogs should be dosed in the morning to coincide with the endogenous cortisol peak.
A single administration may be sufficient for some conditions such as anaphylaxis. Other conditions may require treatment for between two and three weeks. Use the lowest effective dose. Alternate-day therapy should be implemented to control symptoms if possible, to minimise the risks of adrenal insufficiency.
For animals with tumours responsive to corticosteroid therapy, use dose levels based on the surface area of the animal. In some cases, dose levels of 20 mg per m2, reducing to 5 mg per m2, have been found useful.
For oral administration only.
Active Ingredient
Prednidale Tablets 25 mg (100 tablets) ingredients
White, 11 mm circular tablets.
Each tablet contains 25 mg prednisolone.
Side Effects
Side effects of Prednidale Tablets 25 mg (100 tablets)
Do not use in pregnant animals, those suffering from diabetes mellitus, in animals with renal insufficiency or those with corneal ulceration.
Do not use in animals being vaccinated with products containing live organisms. Treatment may render concurrent vaccination inoperative.
Appropriate therapy should be instituted in animals with concurrent bacterial infections. Use of corticosteroids may exacerbate viral infections.
Prolonged use at high dose levels may result in undesirable effects. Do not withdraw corticosteroid therapy suddenly.
Signs of overdosage should be treated symptomatically. Serum electrolytes should be monitored. Consideration should be given to the use of antimicrobials due to the potential suppression of the immune system.
Corticosteroids, including prednisolone, have a wide range of effects. Polydipsia, polyuria and polyphagia may develop, particularly during the early stages of therapy. In the longer term, iatrogenic Cushing?s disease may develop.
Gastrointestinal ulceration has been reported in animals treated with corticosteroids. Steroids may cause enlargement of the liver (hepatomegaly) with increased serum hepatic enzymes.
Corticosteroid therapy may lead to increased time in the healing of wounds and to a reduction in the ability of the body to resist infection. Appropriate anti-infective therapy may be required.
Pharmacologically active dose levels may lead to atrophy of the adrenal cortex, resulting in adrenal insufficiency. This may become apparent particularly after withdrawal of corticosteroid treatment. Adrenal insufficiency may be minimised by institution of alternate-day therapy, if practical. The dosage should be reduced and withdrawn gradually to avoid precipitation of adrenal insufficiency.
Corticosteroids are not recommended for use in pregnant animals. Studies in laboratory animals have shown that administration during early pregnancy may cause foetal abnormalities. Administration during the later stages of pregnancy may cause abortion or early parturition.
Gastrointestinal ulceration may be exacerbated by corticosteroids in animals given non-steroidal anti-inflammatory drugs (NSAIDs).
Regular veterinary re-evaluation of animals on prolonged courses of prednisolone is recommended.
Operator warnings: In the event of accidental ingestion, particularly by a child, seek medical advice and show the doctor the label or the package insert.
Gloves should be worn to administer the product and you should wash hands immediately after administration of the product.
General precautions: For animal treatment only.
Additional Data
Prednidale Tablets 25 mg (100 tablets) specification
| Specification: | Detail: |
|---|---|
| Pack Size: | 100 tablets |
| Brands: | Dechra Veterinary |
| Product Form: | tablet |
| External Link: | http://www.noahcompendium.co.uk/Dechra_Veterinary_Products/documents/S3433.html |
| Strength/Size: | 25 mg |
Reviews
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Service and value for money
Janet Montague-Brown on 12th August 2011
The drugs were despatched as soon as I sent the prescription by e mail. I recieved them in two days .The cost was two thirds lower than the cost of those supplied by my vets. should I need more supplies I will be visiting the site again.
Q & A
- Q. Hi,
My 5 year old cocker spaniel Grace has just been diagnosed with Immune Medicated Haemolytic Anaemia. The vet has prescribed prednicare 6 tablets twice a day and prednidale 2 tablets a day. Is this the best treament for her? - A.
Steroids (like Prednidale and Prednicare) are the mainstay of treatment for IMHA, so yes, it sounds a very appropriate treatment. If she doesn't respond, there are other medications that can be given as well, but its important to start with the steroids first.
David Harris BVSc MRCVS
MyVetMeds - Q. my dog is on prednidale tablets he isdrinking lots more water than normal and passing large amountsof urine should i be worried and take himback to the vet ,
- A.
This is a common side effect of steroids, and not usually a cause for concern. I'd suggest you have a quick chat about it with your vet, because they may want to alter the dose.
David Harris BVSc MRCVS
MyVetMeds - Q. Hi
My Dog is 12 yrs old and has been on quarter prednidale 25mg tablets every other day for 2 yrs. Can you please tell me what the side effects are and what are the other treatments available are for him?
thanks - A.
Steroids like Prednidale have a huge long list of possible side effects, and most dogs will only exhibit a few (if any). The more common ones are weight gain, excess drinking and urinating, hair loss or coat changes, susceptibility to minor infections, and occasionally (especially if combined with non-steroidal antiinflamatories like carprofen or meloxidyl) stomach ulcers. However, I must stress that dogs won't display all of these, and many show almost no side effects at all.
I don't know if there are any other drugs that might help, because I don't know what your dog is being treated for, but that might be something to discuss with your vet. However, in general, steroids are only used long term if there is no other alternative. It is often useful to gradually drop down the dose, until you find the minimum dose which controls the symptoms, and then hold it there, rather than setting a fixed dose and sticking to it -again, that would be worth discussing with your vet.
I hope that helps,
David Harris BVSc MRCVS
MyVetMeds - Q. hi,
Is there a maximum time a dog should be prescirbed this drug and does it cause side effects of loose stools .
Thanks - A.
No, there's no "maximum limit" on how often a dog can use prednisolone although the risk of chronic side effects does increase with longer use.
Gastrointestinal side efffects are relatively common, and diarrhoea is one possibility, especially if it is blood tinged, as steroids like prednidale can cause gut ulcers. That said, slightly loose stools are unlikely to be a sign of a serious side effect.
If you're at all concerned, you should contact your vet; if there is bloody diarrhoea or vomit, you should call them as a matter of urgency.
I hope that helps,
David Harris BVSc MRCVS
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