Equipalazone Oral Powder Sachets 1g (100 sachets)
Equipalazone 1 g oral powder is indicated in the treatment of musculoskeletal disorders in horses and ponies where the anti-inflammatory and analgesic properties of phenylbutazone can offer relief, for example, in lameness associated with osteoarthritic conditions, acute and chronic laminitis, bursitis... Read more
Equipalazone 1 g oral powder is indicated in the treatment of musculoskeletal disorders in horses and ponies where the anti-inflammatory and analgesic properties of phenylbutazone can offer relief, for example, in lameness associated with osteoarthritic conditions, acute and chronic laminitis, bursitis and carpitis, and in the reduction of post-surgical soft tissue reaction.
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Product Description
About Equipalazone Oral Powder Sachets 1g (100 sachets)
Equipalazone 1 g oral powder is indicated in the treatment of musculoskeletal disorders in horses and ponies where the anti-inflammatory and analgesic properties of phenylbutazone can offer relief, for example, in lameness associated with osteoarthritic conditions, acute and chronic laminitis, bursitis and carpitis, and in the reduction of post-surgical soft tissue reaction.
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Directions For Use
Directions for Use
For oral administration only. Dependent on individual response, but as a guide:
Horses: 450 kg (1000 lb) body weight:
Two sachets to be administered twice on day one (equivalent to 8.8 mg/kg/day) followed by one sachet twice daily for four days (4.4 mg/kg/day), then one sachet daily or on alternate days sufficient to keep the horse comfortable (2.2 mg/kg/day).
Ponies: 225 kg (500 lb) body weight:
One sachet (4.4 mg/kg/day) on alternate days.
Adjust dose according to body weight.
Discontinue treatment if no response is evident after four to five days treatment.
Equipalazone 1 g oral powder should be mixed with a small quantity of feed.
Active Ingredient
Equipalazone Oral Powder Sachets 1g (100 sachets) ingredients
Free flowing white/cream powder for oral administration, containing 1 g micro-encapsulated phenylbutazone per sachet.
Preservative: sodium paracombin 0.15 % w/w
Side Effects
Side effects of Equipalazone Oral Powder Sachets 1g (100 sachets)
Not to be used in horses intended for human consumption. Treated horses may never be slaughtered for human consumption. The horse must have been declared as not intended for human consumption under national horse passport legislation.
The therapeutic index of phenylbutazone is low.
Do not exceed the stated dose or the duration of treatment.
Do not use in animals suffering from cardiac, hepatic or renal disease, where there is the possibility of gastrointestinal ulceration or bleeding, or where there is evidence of a blood dyscrasia or hypersensitivity to the product.
Do not administer other NSAIDs concurrently or within 24 hours of each other.
Some NSAIDs may be highly bound to plasma proteins and compete with other highly bound drugs to produce an increase in non-bound pharmacologically active concentrations, which can lead to toxic effects.
Use in any animal less than six weeks of age, or in aged animals, may involve additional risk. If such use cannot be avoided, animals may require a reduced dosage and careful clinical management.
Avoid use in any dehydrated, hypovolaemic or hypotensive animal as there is a risk of increased toxicity.
Concurrent administration of potentially nephrotoxic drugs should be avoided.
It is preferable that NSAIDs which inhibit prostaglandin synthesis are not administered to animals undergoing general anaesthesia until fully recovered.
Gastrointestinal tract ulceration may be exacerbated by corticosteroids in animals given NSAIDs.
Use during pregnancy should be avoided whenever possible, particularly during the first trimester.
Response to long-term therapy should be monitored at regular intervals by a veterinary practitioner.
Additional Data
Equipalazone Oral Powder Sachets 1g (100 sachets) specification
| Specification: | Detail: |
|---|---|
| Pack Size: | 100 sachets |
| Brands: | Dechra Veterinary |
| Product Form: | sachet |
| External Link: | http://www.noahcompendium.co.uk/Dechra_Veterinary_Products/documents/S3407.html |
| Strength/Size: | 1g |
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Q & A
- Q. can equipalazone be given to cattle
- A.
Only "off license" on the cascade - in other words, only if the prescribing vet has decided that there is no licensed and legal medication appropriate for use in that clinical case.
in addition, any animal that has ever been given phenylbutazone (the active ingredient in equipalazone) must be permanently excluded from the food chain, be that milk or meat.
I hope that makes sense,
David Harris BVSc MRCVS
MyVetMeds - Q. Could you please tell me what the withholding period is for a race horse before they can legally race again if taking 1 g of equipalazone
- A.
According to the FEI, bute administered by any route is detectable for approximately 7 days. Because this will vary from horse to horse (due to differences in metabolic rate, exercise, diet/other medications, underlying disease etc), it is the responsibility of the prescribing veterinary surgeon to determine a safe witholding time.
I hope that helps,
David Harris BVSc MRCVS
MyVetMeds - Q. My horse has been having 1 sachet of Equipalazone daily for about 4 months. He has had colic twice very recently, the attacks were only 4 weeks apart. Could this be a side effect of this drug?
- A.
It depends on what caused the colic! Certainly, PBZ (phenylbutazone, the active ingredient in Equipalazone) can cause stomach and probably small intestine irritation and ulcers, so it is a distinct possibility. I can't give a diagnosis over the internet, but if I were you I would discuss the possibility of stomach ulcers with your vet.
Ulcers are very common in horses, especially those in hard training or on drugs like PBZ. Definitive diagnosis requires gastroscopy (looking at the stomach with a flexible 3m telescope); however, often a good clinical examination can tell you that treatment is required. Fortunately, a highly effective treatment (Gastrogard) is available now, so I would strongly suggest you discuss it with your vet.
I hope that helps,
David Harris BVSc MRCVS
MyVetMeds
