Cobactan Powder 4.5% 1.35g 30ml (single pack)
For the treatment of bacterial infections in horses and cattle caused by the following Gram positive and Gram negative microorganisms sensitive to cefquinome:Horses:- Respiratory diseases caused by Streptococcus equi ssp. zooepidemicus.Foals:- Severe bacterial infections with a high risk of septicaemia... Read more
For the treatment of bacterial infections in horses and cattle caused by the following Gram positive and Gram negative microorganisms sensitive to cefquinome:
Horses:
- Respiratory diseases caused by Streptococcus equi ssp. zooepidemicus.
Foals:
- Severe bacterial infections with a high risk of septicaemia in which Escherichia coli is involved.
Cattle:
- Respiratory diseases caused by Pasteurella multocida and Mannheimia haemolytica.
- Digital dermatitis, infectious bulbar necrosis and acute interdigital necrobacillosis (foul in the foot).
- Acute E. coli mastitis with signs of systemic involvement.
Calves:
- E. coli septicaemia.
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Product Description
About Cobactan Powder 4.5% 1.35g 30ml (single pack)
For the treatment of bacterial infections in horses and cattle caused by the following Gram positive and Gram negative microorganisms sensitive to cefquinome:
Horses:
- Respiratory diseases caused by Streptococcus equi ssp. zooepidemicus.
Foals:
- Severe bacterial infections with a high risk of septicaemia in which Escherichia coli is involved.
Cattle:
- Respiratory diseases caused by Pasteurella multocida and Mannheimia haemolytica.
- Digital dermatitis, infectious bulbar necrosis and acute interdigital necrobacillosis (foul in the foot).
- Acute E. coli mastitis with signs of systemic involvement.
Calves:
- E. coli septicaemia.
Please note: images are for illustration purposes only and pack sizes/strengths and new packaging styles may not be reflected in the image shown.
Directions For Use
Directions for Use
Reconstitute the solution for injection by adding the whole contents of the solvent vial. After reconstitution, shake the vial well before use. Do not use another solvent (e.g. water for injection). Swab the rubber stopper before removing each dose. Use a dry sterile needle and syringe. An appropriately graduated syringe must be used to allow accurate administration of the required dose volume. The rubber stopper may be punctured up to 20 times.
See Dosage table: Cobactan 4.5%
at
http://www.noahcompendium.co.uk/Intervet_Schering-Plough/documents/S5659.html
Cattle and calves: by intramuscular injection, and restricted to 10 ml per injection site.
It is recommended to administer the product into different injection sites.
In cattle the preferred injection site is in the muscular tissue of the mid-neck region.
Horses and foals: injections can be given either intramuscularly or intravenously.
In foals, it is recommended to start the treatment with intravenous injections for 3 days and to follow with intramuscular injections.
To ensure the correct dosage and to avoid possible under-dosing, the bodyweight should be determined as accurately as possible.
Active Ingredient
Cobactan Powder 4.5% 1.35g 30ml (single pack) ingredients
Powder and solvent for solution for injection.
1 vial with powder contains:
30 ml vial:
1.35 g cefquinome (as sulphate)
100 ml vial:
4.5 g cefquinome (as sulphate)
1 ml solvent contains:
Preservative:
Benzyl alcohol 10 mg
Each ml of the reconstituted solution contains:
Active substance:
Cefquinome (as sulphate)
45 mg
Excipient:
Benzyl alcohol
10 mg
Side Effects
Side effects of Cobactan Powder 4.5% 1.35g 30ml (single pack)
Do not use in animals which are known to be hypersensitive to cephalosporin antibiotics or other ?-lactam antibiotics.
The safety of Cobactan 4.5% has not been determined in horses and cattle intended for breeding.
Use of the product should be based on susceptibility testing and take into account official and local antimicrobial policies.
Inappropriate use of the product may increase the prevalence of bacteria resistant to cefquinome and may decrease the effectiveness of treatment with cephalosporins, due to the potential for cross-resistance.
Hypersensitivity reactions to cephalosporins occur rarely. In horses, occasionally slight transient reactions may occur at the injection site. In cattle, use of the product may result in localized tissue reaction. Tissue lesions are resolved 15 days after the last injection.
There is no information on reproductive toxicity (incl. teratogenicity) in horses and cattle. Laboratory studies in rats and rabbits have not shown any teratogenic, foetotoxic or maternotoxic effects. Use only according to the benefit:risk assessment by the responsible veterinarian.
Doses of 20 mg/kg in cattle, 1 mg/kg in horses and 3 mg/kg in foals twice daily have been well tolerated.
Operator warnings
Penicillins and cephalosporins may cause hypersensitivity (allergy) following injection, inhalation, ingestion or skin contact. Hypersensitivity to penicillins may lead to cross sensitivity to cephalosporins and vice versa. Allergic reactions to these substances may occasionally be serious.
1. Do not handle this product if you know you are sensitized, or if you have been advised not to work with such preparations.
2. Handle this product with great care to avoid exposure, taking all recommended precautions.
3. If you develop symptoms following exposure such as a skin rash, you should seek medical advice and show the doctor this warning. Swelling of the face, lips or eyes or difficulty with breathing, are more serious symptoms and require urgent medical attention.
In case of accidental contact with eyes, rinse immediately with copious amounts of water. Accidental spillage on the skin should be washed off immediately with soap and water. In case of accidental self-injection, seek medical advice immediately and show the package leaflet or the label to the physician.
Withdrawal periods
Horse
Horse meat: 4 days.
Not to be used in horses producing milk for human consumption.
Cattle
Meat: 2 days.
Milk: 36 hours (3 milkings).
For animal treatment only. Keep out of the reach and sight of children.
Additional Data
Cobactan Powder 4.5% 1.35g 30ml (single pack) specification
| Specification: | Detail: |
|---|---|
| Pack Size: | single pack |
| Brands: | Intervet |
| Product Form: | injection |
| External Link: |
http://www.noahcompendium.co.uk/MSD_Animal_Health/documents/S5659.html |
| Strength/Size: | 4.5% 1.35 g |
