Domosedan Gel 7.5mg/ml 3ml
DORMOSEDAN GEL® (detomidine hydrochloride) is a convenient solution when your horses occasionally need a mild, standing sedative prior to certain stressful situations or minor, (nonpainful) husbandry procedures.
Obtained only through a veterinary prescription, DORMOSEDAN GEL is a single-dose... Read more
DORMOSEDAN GEL® (detomidine hydrochloride) is a convenient solution when your horses occasionally need a mild, standing sedative prior to certain stressful situations or minor, (nonpainful) husbandry procedures.
Obtained only through a veterinary prescription, DORMOSEDAN GEL is a single-dose syringe and is easy enough for horse owners to administer themselves.
If you've ever had to shoe, groom or clean the sheath of a horse that doesn't stand still, you'll appreciate this sedative almost as much as the horse.
Visit www.myvetmeds.co.uk / equine / sedative-equine / domosedan-gel-7-5mg-ml-3ml.htm
Product Description
About Domosedan Gel 7.5mg/ml 3ml
DORMOSEDAN GEL® (detomidine hydrochloride) is a convenient solution when your horses occasionally need a mild, standing sedative prior to certain stressful situations or minor, (nonpainful) husbandry procedures.
Obtained only through a veterinary prescription, DORMOSEDAN GEL is a single-dose syringe and is easy enough for horse owners to administer themselves.
If you've ever had to shoe, groom or clean the sheath of a horse that doesn't stand still, you'll appreciate this sedative almost as much as the horse.
Please note: images are for illustration purposes only and pack sizes/strengths and new packaging styles may not be reflected in the image shown.
Directions For Use
Directions for Use
DORMOSEDAN GEL® (detomidine hydrochloride) is administered sublingually at 40 mcg/kg (18 mcg/lb), and the dosing syringe delivers the product in 0.25 mL increments. The dosing syringe is intended for one-time use and then properly discarded. The following dosing table provides the dose volume to be administered for the corresponding body weight in 0.25 mL increments.
Onset and duration of sedation
The duration and level of sedation are dose dependent. At the recommended 40 mcg/kg dose, the onset of sedation was observed at approximately 40 minutes with a duration of sedation lasting between 90 to 180 minutes.
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Active Ingredient
Domosedan Gel 7.5mg/ml 3ml ingredients
What are the pharmacokinetic parameters of DORMOSEDAN GEL?
- Mean peak concentration (Cmax) = 4.3 ng/mL
- Mean time to reach Cmax (Tmax) = 1.8 hours (range from 1 to 3 hours)
- Bioavailability = ~22%
- Volume of distribution (Vd) varies between 0.69 L/kg and 1.89 L/kg
- Estimated half-life of elimination (T½) = 1.27 hours
- Protein binding ≈ 85%
Side Effects
Side effects of Domosedan Gel 7.5mg/ml 3ml
Important Safety Information
DORMOSEDAN GEL is contraindicated in horses with known hypersensitivity to detomidine. Intravenous potentiated sulfonamides should not be used in anesthetized or sedated horses, as potentially fatal dysrhythmias may occur. Do not use DORMOSEDAN GEL in horses with pre-existing atrioventricular (AV) or sinoatrial (SA) blocks, cardiovascular disease, respiratory disorders, liver or kidney diseases, or in conditions of shock, severe debilitation or stress due to extreme heat, cold, fatigue or high altitude. Appropriate precautions should be taken while handling and using gel-dosing syringes, as DORMOSEDAN GEL can be absorbed following direct exposure to skin, eyes or mouth, and may cause irritation. The use of impermeable gloves is advised. Please click here for the full prescribing information.
Additional Data
Domosedan Gel 7.5mg/ml 3ml specification
| Specification: | Detail: |
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| Brands: | Pfizer |
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